CPNE8 Gene Summary [Human]
Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene is one of several genes that encode a calcium-dependent protein containing two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. [provided by RefSeq, Jul 2008]
Details
| Type | Processed Transcript |
| Official Symbol | CPNE8 |
| Official Name | copine 8 [Source:HGNC Symbol;Acc:HGNC:23498] |
| Ensembl ID | ENSG00000139117 |
| Bio databases IDs | |
| Aliases | copine 8 |
| Synonyms | 1200003E11RIK, 1500031E20Rik, copine 8, copine VIII |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CPNE8 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Copine
- von Willebrand factor (vWF) type A domain
- vWFA
- protein binding
- Protein kinase C conserved region 2 (CalB)
- C2 domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human CPNE8 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cellular response to calcium ion
Cellular Component
Where in the cell the gene product is active
- extracellular vesicular exosome
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- metal ion binding
- calcium-dependent phospholipid binding