TLNRD1 Gene Summary [Human]
This gene encodes a protein that is regulated by micro RNA MiR-574-3, and is thought to have an oncogenic function in human bladder cancer. A similar gene in mouse is located in a chromosomal region critical for differentiation of mesoderm, which affects embryo patterning and the formation of heart, muscle, blood, skeleton and the urogenital system. The mouse gene is expressed in early development, and in the adult. [provided by RefSeq, Nov 2016]
Details
| Type | Protein Coding |
| Official Symbol | TLNRD1 |
| Official Name | talin rod domain containing 1 [Source:HGNC Symbol;Acc:HGNC:13519] |
| Ensembl ID | ENSG00000140406 |
| Bio databases IDs | |
| Aliases | talin rod domain containing 1 |
| Synonyms | MESDC1, talin rod domain containing 1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TLNRD1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- actin binding
- protein binding
- identical protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- actin stress fibers
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TLNRD1 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- stress fiber
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding
- actin binding