Tlnrd1 Gene Summary [Mouse]

Enables actin binding activity. Colocalizes with stress fiber. Is expressed in several structures, including 4-cell stage embryo; genitourinary system; liver; lung; and spleen. Orthologous to human TLNRD1 (talin rod domain containing 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Tlnrd1
Official Name
talin rod domain containing 1 [Source:MGI Symbol;Acc:MGI:1891420]
Ensembl ID
ENSMUSG00000070462
Bio databases IDs NCBI: 80889 Ensembl: ENSMUSG00000070462
Aliases talin rod domain containing 1
Synonyms MESDC1, talin rod domain containing 1
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tlnrd1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • actin binding
  • protein binding
  • identical protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
  • lipopolysaccharide
  • prostaglandin E2
  • IL1B

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • actin stress fibers

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Tlnrd1 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • stress fiber

Molecular Function

What the gene product does at the molecular level
  • identical protein binding
  • protein binding
  • actin binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.