This gene encodes a member of the aquaglyceroporin family of integral membrane proteins. Members of this family function as water-permeable channels in the epithelia of organs that absorb and excrete water. This protein was shown to function as a water-selective channel, and could also permeate neutral solutes such as glycerol and urea. [provided by RefSeq, Jul 2008]
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
MIP
glycerol channel
protein binding
water channel
transporter
Pathways
Biological processes and signaling networks where the AQP10 gene plays a role, providing insight into its function and relevance in health or disease.
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
CUL3
PLP1
GPR37L1
GPR152
CISD2
CYBC1
ERGIC3
PVR
MGST3
LMNA
disease
non-insulin-dependent diabetes mellitus
metabolic syndrome X
regulated by
isoproterenol
regulates
glycerol
water
role in cell
permeability
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
Plasma Membrane
intracellular membrane-bounded organelle
cellular membrane
apical membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the AQP10 gene, providing context for its role in the cell.
BIOLOGICAL PROCESS
Functions and activities the gene product is involved in
water transport
protein homotetramerization
glycerol transport
urea transmembrane transport
cellular response to acidity
response to toxin
CELLULAR COMPONENT
Where in the cell the gene product is active
lipid particle
intracellular membrane-bounded organelle
basolateral plasma membrane
plasma membrane
apical plasma membrane
MOLECULAR FUNCTION
What the gene product does at the molecular level
protein binding
glycerol channel activity
water channel activity
urea transmembrane transporter activity
Gene-Specific Assays for Results You Can Trust
Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.