PHOSPHO2 Gene Summary [Human]

Predicted to enable phosphatase activity. Predicted to be involved in dephosphorylation. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
PHOSPHO2
Official Name
phosphatase, orphan 2 [Source:HGNC Symbol;Acc:HGNC:28316]
Ensembl ID
ENSG00000144362
Bio databases IDs NCBI: 493911 Ensembl: ENSG00000144362
Aliases phosphatase, orphan 2
Synonyms 1700048E23RIK, AV006103, Phos2, phosphatase, orphan 2
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human PHOSPHO2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like
  • phosphoserine phosphatase SerB
  • protein binding
  • 2,3-diketo-5-methylthio-1-phosphopentane phosphatase
  • Haloacid Dehalogenase-like Hydrolases
  • haloacid dehalogenase-like hydrolase

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • androgenic alopecia
  • chronic lymphocytic leukemia

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human PHOSPHO2 gene, providing context for its role in the cell.

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • metal ion binding
  • phosphatase activity
  • pyridoxal phosphatase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.