METTL21A Gene Summary [Human]
Enables ATPase binding activity; Hsp70 protein binding activity; and protein-lysine N-methyltransferase activity. Involved in peptidyl-lysine methylation. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | METTL21A |
| Official Name | methyltransferase like 21A [Source:HGNC Symbol;Acc:HGNC:30476] |
| Ensembl ID | ENSG00000144401 |
| Bio databases IDs | |
| Aliases | methyltransferase like 21A, methyltransferase 21A, HSPA lysine, Hepatocellular carcinoma-associated antigen 557b, heat shock protein 70kDa lysine (K) methyltransferase |
| Synonyms | 2310038H17Rik, FAM119A, HCA557b, HSPA-KMT, methyltransferase 21A, HSPA lysine, RGD1311824 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human METTL21A often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein-lysine N-methyltransferase
- protein methyltransferase
- ATPase binding
- Hsp70 protein binding
- heat shock protein binding
- enzyme
- protein binding
- AdoMet_MTases
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human METTL21A gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- chromatin remodeling
- peptidyl-lysine methylation
- regulation of ATPase activity
- protein methylation
Cellular Component
Where in the cell the gene product is active
- cytosol
- macromolecular complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- heat shock protein binding
- protein binding
- protein methyltransferase activity
- histone methyltransferase activity
- protein-lysine N-methyltransferase activity
- ATPase binding
- Hsp70 protein binding