FAM50B Gene Summary [Human]
This gene contains an intronless ORF that arose from ancestral retroposition. The encoded protein is related to a plant protein that plays a role in the circadian clock. This gene is adjacent to a differentially methylated region (DMR) and is imprinted and paternally expressed in many tissues. [provided by RefSeq, Nov 2015]
Details
| Type | Protein Coding |
| Official Symbol | FAM50B |
| Official Name | family with sequence similarity 50 member B [Source:HGNC Symbol;Acc:HGNC:18789] |
| Ensembl ID | ENSG00000145945 |
| Bio databases IDs | |
| Aliases | family with sequence similarity 50 member B, XAP5 like |
| Synonyms | D0H6S2654E, D6S2654E, family with sequence similarity 50 member B, family with sequence similarity 50, member B, LOC124906553, RGD1563458, RP11 420L94, X5L, XAP-5-like |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human FAM50B often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- XAP5, circadian clock regulator
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- midbody
- cytoplasmic bridges
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human FAM50B gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- chromatin organization
Cellular Component
Where in the cell the gene product is active
- nucleus
- intercellular bridge
- midbody
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding