Fam50b Gene Summary [Mouse]

Predicted to be involved in chromatin organization. Predicted to be located in intercellular bridge; midbody; and nucleoplasm. Predicted to be active in nucleus. Is expressed in primary spermatocyte; seminiferous tubule; and spermatid. Orthologous to human FAM50B (family with sequence similarity 50 member B). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Fam50b
Official Name
family with sequence similarity 50, member B [Source:MGI Symbol;Acc:MGI:1351640]
Ensembl ID
ENSMUSG00000038246
Bio databases IDs NCBI: 108161 Ensembl: ENSMUSG00000038246
Aliases family with sequence similarity 50, member B
Synonyms D0H6S2654E, D6S2654E, family with sequence similarity 50 member B, family with sequence similarity 50, member B, LOC124906553, RGD1563458, RP11 420L94, X5L, XAP-5-like
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Fam50b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding
  • XAP5, circadian clock regulator

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • colon cancer
  • bladder cancer
  • melanoma
  • melanoma cancer
role in cell
  • formation
  • formation in
  • fitness

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • midbody
  • cytoplasmic bridges
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Fam50b gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • chromatin organization

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • intercellular bridge
  • midbody
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

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