INIP Gene Summary [Human]
The protein encoded by this gene is a subunit of single-stranded DNA binding complexes that are important for maintaining genome stability. These complexes are involved in G2/M checkpoint control and homologous recombination repair. [provided by RefSeq, Jul 2016]
Details
| Type | Protein Coding |
| Official Symbol | INIP |
| Official Name | INTS3 and NABP interacting protein [Source:HGNC Symbol;Acc:HGNC:24994] |
| Ensembl ID | ENSG00000148153 |
| Bio databases IDs | |
| Aliases | INTS3 and NABP interacting protein, hSSB-interacting protein 1, sensor of single-strand DNA complex subunit C, minute INTS3/hSSB-associated element |
| Synonyms | 1110054O05Rik, 2610312O17Rik, C9orf80, HSPC043, hSSBIP1, INTS3 and NABP interacting protein, MISE, RGD1307983, SOSSC, SSBIP1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human INIP often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- SOSS complex subunit C
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human INIP gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- DNA repair
- double-strand break repair via homologous recombination
- response to DNA damage stimulus
- response to ionizing radiation
Cellular Component
Where in the cell the gene product is active
- nucleus
- site of double-strand break
- SOSS complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding