Inip Gene Summary [Mouse]

Predicted to be involved in double-strand break repair via homologous recombination; mitotic G2/M transition checkpoint; and response to ionizing radiation. Predicted to be located in nucleus and site of double-strand break. Predicted to be part of SOSS complex. Predicted to be active in nucleoplasm. Is expressed in several structures, including brain ventricular layer; submandibular gland primordium; thymus primordium; tooth; and vibrissa. Orthologous to human INIP (INTS3 and NABP interacting protein). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Inip
Official Name
INTS3 and NABP interacting protein [Source:MGI Symbol;Acc:MGI:1913459]
Ensembl ID
ENSMUSG00000038544
Bio databases IDs NCBI: 66209 Ensembl: ENSMUSG00000038544
Aliases INTS3 and NABP interacting protein
Synonyms 1110054O05Rik, 2610312O17Rik, C9orf80, HSPC043, hSSBIP1, INTS3 and NABP interacting protein, MISE, RGD1307983, SOSSC, SSBIP1
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Inip often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • SOSS complex subunit C
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • specific language impairment
regulated by
role in cell
  • phosphorylation in
  • cell death
  • serine phosphorylation in
  • threonine phosphorylation in
  • stability
  • DNA damage response

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Inip gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • DNA repair
  • double-strand break repair via homologous recombination
  • response to DNA damage stimulus
  • response to ionizing radiation

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • site of double-strand break
  • SOSS complex
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.