GPR107 Gene Summary [Human]

Predicted to enable clathrin heavy chain binding activity. Predicted to be involved in clathrin-dependent endocytosis. Located in Golgi apparatus and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
GPR107
Official Name
G protein-coupled receptor 107 [Source:HGNC Symbol;Acc:HGNC:17830]
Ensembl ID
ENSG00000148358
Bio databases IDs NCBI: 57720 Ensembl: ENSG00000148358
Aliases G protein-coupled receptor 107
Synonyms 9930033D15RIK, bA138E2.2, C530034M11, GCDRP, G protein-coupled receptor 107, LUSTR1, mKIAA1624
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human GPR107 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • G-protein coupled receptor
  • Lung seven transmembrane receptor
  • clathrin binding
  • protein binding

Pathways

Biological processes and signaling networks where the GPR107 gene in human plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • Huntington disease
regulated by
  • FAS
  • neutrophils
  • camptothecin

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cellular membrane
  • Golgi Apparatus
  • nucleoplasm
  • early endosomes
  • clathrin-coated vesicles

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human GPR107 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • clathrin-mediated endocytosis

Cellular Component

Where in the cell the gene product is active
  • early endosome
  • membrane
  • Golgi apparatus
  • clathrin-coated vesicle
  • plasma membrane
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • clathrin heavy chain binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.