Gpr107 Gene Summary [Mouse]
Enables clathrin heavy chain binding activity. Acts upstream of or within clathrin-dependent endocytosis. Located in clathrin-coated vesicle and early endosome. Orthologous to human GPR107 (G protein-coupled receptor 107). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Gpr107 |
| Official Name | G protein-coupled receptor 107 [Source:MGI Symbol;Acc:MGI:2139054] |
| Ensembl ID | ENSMUSG00000000194 |
| Bio databases IDs | |
| Aliases | G protein-coupled receptor 107 |
| Synonyms | 9930033D15RIK, bA138E2.2, C530034M11, GCDRP, G protein-coupled receptor 107, LUSTR1, mKIAA1624 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Gpr107 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- G-protein coupled receptor
- Lung seven transmembrane receptor
- clathrin binding
- protein binding
Pathways
Biological processes and signaling networks where the Gpr107 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
- Golgi Apparatus
- nucleoplasm
- early endosomes
- clathrin-coated vesicles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Gpr107 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- clathrin-mediated endocytosis
Cellular Component
Where in the cell the gene product is active
- early endosome
- membrane
- Golgi apparatus
- clathrin-coated vesicle
- plasma membrane
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- clathrin heavy chain binding