RAD9B Gene Summary [Human]
Predicted to be involved in DNA integrity checkpoint signaling; DNA repair; and cellular response to ionizing radiation. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Processed Transcript |
| Official Symbol | RAD9B |
| Official Name | RAD9 checkpoint clamp component B [Source:HGNC Symbol;Acc:HGNC:21700] |
| Ensembl ID | ENSG00000151164 |
| Bio databases IDs | |
| Aliases | RAD9 checkpoint clamp component B |
| Synonyms | A630082N15RIK, RAD9 checkpoint clamp component B |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RAD9B often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- beta_clamp
- Rad9
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human RAD9B gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- DNA repair
- DNA replication checkpoint
- cellular response to ionizing radiation
- intra-S DNA damage checkpoint
Cellular Component
Where in the cell the gene product is active
- nucleus
- checkpoint clamp complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding