TADA1 Gene Summary [Human]
TADA1L is a protein subunit of the human STAGA complex (SPT3; (MIM 602947)/TAF9 (MIM 600822)/GCN5 (MIM 602301) acetyltransferase complex), which is a chromatin-modifying multiprotein complex (Martinez et al., 2001 [PubMed 11564863]).[supplied by OMIM, Apr 2009]
Details
| Type | Processed Transcript |
| Official Symbol | TADA1 |
| Official Name | transcriptional adaptor 1 [Source:HGNC Symbol;Acc:HGNC:30631] |
| Ensembl ID | ENSG00000152382 |
| Bio databases IDs | |
| Aliases | transcriptional adaptor 1 |
| Synonyms | 2900026B15Rik, ADA1, D1Ertd251e, hADA1, HFI1, RGD1306774, STAF42, STAF42 alpha, STAF42 α, TADA1L, transcriptional adaptor 1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TADA1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- histone fold domain (HFD) superfamily
- transcription regulator
- transcription co-activator
- protein binding
- Transcriptional regulator of RNA polII, SAGA, subunit
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- focal adhesions
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TADA1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of transcription, DNA-dependent
- regulation of RNA splicing
- regulation of DNA repair
- regulation of transcription from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- nucleus
- focal adhesion
- cytosol
- SAGA complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- transcription coactivator activity