SRP19 Gene Summary [Human]

Enables 7S RNA binding activity. Contributes to ribosome binding activity. Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition. Located in nucleolus. Part of signal recognition particle, endoplasmic reticulum targeting. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
SRP19
Official Name
signal recognition particle 19 [Source:HGNC Symbol;Acc:HGNC:11300]
Ensembl ID
ENSG00000153037
Bio databases IDs NCBI: 6728 Ensembl: ENSG00000153037
Aliases signal recognition particle 19
Synonyms 2310020D23Rik, CTC 487M238, signal recognition particle 19
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SRP19 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • 7S RNA binding
  • SRP19 protein
  • ribosome binding
  • protein binding
  • RNA binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • breast cancer
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • Cytoplasm
  • cytosol
  • nucleoplasm
  • nucleoli
  • nuclear bodies

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human SRP19 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cotranslational protein targeting to membrane
  • SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition

Cellular Component

Where in the cell the gene product is active
  • nuclear body
  • signal recognition particle
  • cytosol
  • nucleolus
  • signal recognition particle, endoplasmic reticulum targeting

Molecular Function

What the gene product does at the molecular level
  • RNA binding
  • protein binding
  • ribosome binding
  • 7S RNA binding

Gene-Specific Assays for Results You Can Trust

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