TRMT44 Gene Summary [Human]
The protein encoded by this gene is a putative tRNA methyltransferase found in the cytoplasm. Defects in this gene may be a cause of partial epilepsy with pericentral spikes (PEPS), but that has not been proven definitively. [provided by RefSeq, May 2012]
Details
| Type | Retained Intron |
| Official Symbol | TRMT44 |
| Official Name | tRNA methyltransferase 44 homolog [Source:HGNC Symbol;Acc:HGNC:26653] |
| Ensembl ID | ENSG00000155275 |
| Bio databases IDs | |
| Aliases | tRNA methyltransferase 44 homolog |
| Synonyms | 2310079F23Rik, C4orf23, FLJ12891, METTL19, RGD1308380, TRM44, tRNA methyltransferase 44, tRNA methyltransferase 44 homolog |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TRMT44 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- AdoMet_MTases
- Predicted AdoMet-dependent methyltransferase
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TRMT44 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- tRNA methylation
Cellular Component
Where in the cell the gene product is active
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- metal ion binding
- tRNA (uracil) methyltransferase activity