GPR61
GPR61 Gene Summary
This gene belongs to the G-protein coupled receptor 1 family. G protein-coupled receptors contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. The protein encoded by this gene is most closely related to biogenic amine receptors. [provided by RefSeq, Jul 2008]
Details
| Type | Protein Coding |
| Official Symbol | GPR61 |
| Official Name | G protein-coupled receptor 61 [Source:HGNC Symbol;Acc:HGNC:13300] |
| Ensembl ID | ENSG00000156097 |
| Bio databases IDs | |
| Aliases | G protein-coupled receptor 61 |
| Synonyms | BALGR,GPCR3,G protein-coupled receptor 61 |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- G-protein coupled receptor
- 7 transmembrane receptor (rhodopsin family)
- protein binding
- seven-transmembrane G protein-coupled receptor superfamily
Pathways
Biological processes and signaling networks where the GPR61 gene plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
- SCN3B
- EMP3
- PLP1
- FCER1G
- APP
- STRIT1
- PMP22
- TRARG1
- TMEM218
- SLC13A4
disease
- gallstone
regulated by
- cisplatin
- TP53
- PTEN
- RB1
regulates
role in cell
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
- endosomes
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the GPR61 gene, providing context for its role in the cell.
BIOLOGICAL PROCESS
Functions and activities the gene product is involved in
- G-protein coupled receptor signaling pathway
- G-protein coupled receptor signaling in absence of ligand
CELLULAR COMPONENT
Where in the cell the gene product is active
- endosome
- receptor complex
- endosome membrane
- plasma membrane
MOLECULAR FUNCTION
What the gene product does at the molecular level
- G-protein coupled receptor activity
- protein binding