Gpr61 Gene Summary [Mouse]

Predicted to enable G protein-coupled receptor activity and arrestin family protein binding activity. Predicted to be involved in ligand-independent adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to be located in endosome membrane. Predicted to be part of receptor complex. Predicted to be active in endosome and plasma membrane. Orthologous to human GPR61 (G protein-coupled receptor 61). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Gpr61
Official Name
G protein-coupled receptor 61 [Source:MGI Symbol;Acc:MGI:2441719]
Ensembl ID
ENSMUSG00000046793
Bio databases IDs NCBI: 229714 Ensembl: ENSMUSG00000046793
Aliases G protein-coupled receptor 61
Synonyms BALGR, GPCR3, G protein-coupled receptor 61
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Gpr61 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • G-protein coupled receptor
  • 7 transmembrane receptor (rhodopsin family)
  • protein binding
  • seven-transmembrane G protein-coupled receptor superfamily

Pathways

Biological processes and signaling networks where the Gpr61 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • gallstone
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cellular membrane
  • endosomes

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Gpr61 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • G-protein coupled receptor signaling pathway
  • G-protein coupled receptor signaling in absence of ligand

Cellular Component

Where in the cell the gene product is active
  • endosome
  • receptor complex
  • endosome membrane
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • G-protein coupled receptor activity
  • protein binding

Gene-Specific Assays for Results You Can Trust

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