DPY19L4 Gene Summary [Human]

Predicted to enable mannosyltransferase activity. Predicted to be involved in protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan. Predicted to be integral component of membrane. Predicted to be active in nuclear inner membrane. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
DPY19L4
Official Name
dpy-19 like 4 [Source:HGNC Symbol;Acc:HGNC:27829]
Ensembl ID
ENSG00000156162
Bio databases IDs NCBI: 286148 Ensembl: ENSG00000156162
Aliases dpy-19 like 4
Synonyms dpy-19 like 4, Gm1023, LOC203107, LOC286148, Narg3, RGD1305828
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human DPY19L4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • C-mannosyltransferase Dpy19
  • protein binding
  • Q-cell neuroblast polarization

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • hypertrophic cardiomyopathy
  • non-insulin-dependent diabetes mellitus
  • age-related hearing loss
  • gout
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human DPY19L4 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan

Cellular Component

Where in the cell the gene product is active
  • nuclear inner membrane

Molecular Function

What the gene product does at the molecular level
  • mannosyltransferase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.