MALSU1 Gene Summary [Human]
Predicted to enable ribosomal large subunit binding activity. Involved in negative regulation of mitochondrial translation and ribosomal large subunit biogenesis. Located in cytosol and mitochondrion. Colocalizes with mitochondrial large ribosomal subunit. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Processed Transcript |
| Official Symbol | MALSU1 |
| Official Name | mitochondrial assembly of ribosomal large subunit 1 [Source:HGNC Symbol;Acc:HGNC:21721] |
| Ensembl ID | ENSG00000156928 |
| Bio databases IDs | |
| Aliases | mitochondrial assembly of ribosomal large subunit 1 |
| Synonyms | 2410003K15Rik, C7orf30, MASU1, Matsu1, mitochondrial assembly of ribosomal large subunit 1, mtRsfA, RGD1306936 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human MALSU1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Ribosomal silencing factor during starvation
- ribosome binding
- protein binding
- ribosomal large subunit binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- Mitochondria
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human MALSU1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of mitochondrial translation
- ribosomal large subunit biogenesis
- negative regulation of translation
- negative regulation of ribosome biogenesis
Cellular Component
Where in the cell the gene product is active
- mitochondrial matrix
- mitochondrion
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding
- ribosomal large subunit binding