STARD9 Gene Summary [Human]
Enables microtubule binding activity and microtubule motor activity. Involved in spindle assembly. Located in centriole; cytoplasm; and nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Retained Intron |
| Official Symbol | STARD9 |
| Official Name | StAR related lipid transfer domain containing 9 [Source:HGNC Symbol;Acc:HGNC:19162] |
| Ensembl ID | ENSG00000159433 |
| Bio databases IDs | |
| Aliases | StAR related lipid transfer domain containing 9 |
| Synonyms | 4831403C07RIK, E230025N21Rik, FLJ21936, KIF16A, LOC100363887, LOC645106, LOC645111, LOC688021, LOC688023, mKIAA1300, RGD1310448, StAR-related lipid transfer domain containing 9 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human STARD9 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- SRPBCC domain
- Kinesin motor, catalytic domain
- microtubule binding
- Inner membrane component of T3SS, cytoplasmic domain
- Ezrin/radixin/moesin, alpha-helical domain
- Myosin and Kinesin motor domain
- FHA domain
- Kinesin motor domain
- motor domain
- microtubule motor protein
- Kinesin-associated
- forkhead associated (FHA) domain superfamily
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- coronary artery disease
- bipolar disorder
- suicide attempt
- pervasive developmental disorder
- bipolar I disorder
regulated by
- CYP1B1
- valproic acid
- ETV6-RUNX1
role in cell
- apoptosis
- generation in
- fragmentation in
- fragmentation
- assembly
- generation
- mitosis
- spindle checkpoint in
- misalignment in
- misalignment
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- daughter centriole
- Nucleus
- centrosome
- centriole
- spindle pole
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human STARD9 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- spindle assembly
- microtubule-based movement
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- centriole
Molecular Function
What the gene product does at the molecular level
- ATP binding
- microtubule motor activity
- lipid binding
- microtubule binding