SCGB3A2 Gene Summary [Human]
The protein encoded by this gene is a secreted lung surfactant protein and a downstream target of thyroid transcription factor. A single nucleotide polymorphism in the promoter of this gene results in susceptibility to asthma.[provided by RefSeq, Mar 2010]
Details
| Type | Protein Coding |
| Official Symbol | SCGB3A2 |
| Official Name | secretoglobin family 3A member 2 [Source:HGNC Symbol;Acc:HGNC:18391] |
| Ensembl ID | ENSG00000164265 |
| Bio databases IDs | |
| Aliases | secretoglobin family 3A member 2, uteroglobin-related protein 1, pneumo secretory protein 1, uteroglobin related protein 1 |
| Synonyms | LU103, LuLeu1, PNSP1, secretoglobin family 3A member 2, secretoglobin, family 3A, member 2, UGRP1, Utgrp1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SCGB3A2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Secretoglobin 3A
- protein binding
- Secretoglobin
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- pulmonary fibrosis
- susceptibility to asthma
role in cell
- expression in
- phosphorylation in
- differentiation
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- Cytoplasm
- cell surface
- organelle lumens
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SCGB3A2 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- extracellular space
- endocytic vesicle lumen
- extracellular region