RELL2 Gene Summary [Human]

Predicted to enable collagen binding activity. Involved in positive regulation of p38MAPK cascade. Predicted to be located in extracellular matrix. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
RELL2
Official Name
RELT like 2 [Source:HGNC Symbol;Acc:HGNC:26902]
Ensembl ID
ENSG00000164620
Bio databases IDs NCBI: 285613 Ensembl: ENSG00000164620
Aliases RELT like 2
Synonyms 4631403P03Rik, C5orf16, ependolin, LOC102724138, RELT-like 2, RGD1305276
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RELL2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • collagen binding
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
role in cell
  • proliferation
  • apoptosis
  • gemcitabine sensitivity

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • extracellular matrix
  • basement membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human RELL2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • positive regulation of cell-substrate adhesion
  • positive regulation of p38MAPK cascade

Cellular Component

Where in the cell the gene product is active
  • basement membrane
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • collagen binding

Gene-Specific Assays for Results You Can Trust

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