Rell2 Gene Summary [Mouse]
Enables collagen binding activity. Acts upstream of or within positive regulation of cell-substrate adhesion. Located in basement membrane. Is expressed in lip; lower jaw molar dental lamina; lower jaw molar enamel organ; and oral epithelium. Orthologous to human RELL2 (RELT like 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | Rell2 |
| Official Name | RELT-like 2 [Source:MGI Symbol;Acc:MGI:1918044] |
| Ensembl ID | ENSMUSG00000044024 |
| Bio databases IDs | |
| Aliases | RELT-like 2 |
| Synonyms | 4631403P03Rik, C5orf16, ependolin, LOC102724138, RELT-like 2, RGD1305276 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rell2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- collagen binding
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- extracellular matrix
- basement membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rell2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of cell-substrate adhesion
- positive regulation of p38MAPK cascade
Cellular Component
Where in the cell the gene product is active
- basement membrane
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- collagen binding