GPR146 Gene Summary [Human]

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
GPR146
Official Name
G protein-coupled receptor 146 [Source:HGNC Symbol;Acc:HGNC:21718]
Ensembl ID
ENSG00000164849
Bio databases IDs NCBI: 115330 Ensembl: ENSG00000164849
Aliases G protein-coupled receptor 146
Synonyms BC003323, D830046C22Rik, G protein-coupled receptor 146, PGR8, RGD1560731
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human GPR146 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • G-protein coupled receptor
  • 7 transmembrane receptor (rhodopsin family)
  • seven-transmembrane G protein-coupled receptor superfamily

Pathways

Biological processes and signaling networks where the GPR146 gene in human plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • COVID-19
regulated by
regulates
  • cholesterol
  • cyclic AMP
  • Vsvg
role in cell
  • expression in
  • replication in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cellular membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human GPR146 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • G-protein coupled receptor signaling pathway

Cellular Component

Where in the cell the gene product is active
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • G-protein coupled receptor activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.