C11orf65 Gene Summary [Human]
Predicted to be involved in negative regulation of mitochondrial fission and negative regulation of protein targeting to mitochondrion. Predicted to be located in cytosol and mitochondrial outer membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | C11orf65 |
| Official Name | chromosome 11 open reading frame 65 [Source:HGNC Symbol;Acc:HGNC:28519] |
| Ensembl ID | ENSG00000166323 |
| Bio databases IDs | |
| Aliases | chromosome 11 open reading frame 65, mitochondrial fission factor interactor |
| Synonyms | 4930550C14Rik, C8h11orf65, chromosome 11 open reading frame 65, Mff interactor, Mfi, RGD1311251, RIKEN cDNA 4930550C14 gene, similar to human chromosome 11 open reading frame 65 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human C11orf65 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- cytosol
- mitochondrial outer membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human C11orf65 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of mitochondrial fission
Cellular Component
Where in the cell the gene product is active
- cytosol
- mitochondrial outer membrane
Molecular Function
What the gene product does at the molecular level
- protein binding