GARRE1 Gene Summary [Human]
Enables CCR4-NOT complex binding activity and small GTPase binding activity. Involved in Rac protein signal transduction. Located in P-body. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | GARRE1 |
| Official Name | granule associated Rac and RHOG effector 1 [Source:HGNC Symbol;Acc:HGNC:29016] |
| Ensembl ID | ENSG00000166398 |
| Bio databases IDs | |
| Aliases | granule associated Rac and RHOG effector 1 |
| Synonyms | 4931406P16Rik, granule associated Rac and RHOG effector 1, KIAA0355, MiniBAR, mKIAA0355, RGD1308428 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human GARRE1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- binding protein
- enzyme binding
- protein binding
- Domain of unknown function (DUF4745)
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- cytoplasmic mRNA processing body
- cytosol
- plasma
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human GARRE1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- Rac protein signal transduction
Cellular Component
Where in the cell the gene product is active
- cytoplasmic mRNA processing body
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding
- small GTPase binding