Garre1 Gene Summary [Mouse]

Predicted to enable CCR4-NOT complex binding activity and small GTPase binding activity. Predicted to be involved in Rac protein signal transduction. Predicted to be located in P-body. Is expressed in lung and ovary. Orthologous to human GARRE1 (granule associated Rac and RHOG effector 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Garre1
Official Name
granule associated Rac and RHOG effector 1 [Source:MGI Symbol;Acc:MGI:1924311]
Ensembl ID
ENSMUSG00000066571
Bio databases IDs NCBI: 233103 Ensembl: ENSMUSG00000066571
Aliases granule associated Rac and RHOG effector 1
Synonyms 4931406P16Rik, granule associated Rac and RHOG effector 1, KIAA0355, MiniBAR, mKIAA0355, RGD1308428
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Garre1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • binding protein
  • enzyme binding
  • protein binding
  • Domain of unknown function (DUF4745)

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • colorectal cancer
  • myopathy
regulated by
  • Influenza A virus (A/Bangkok/RX73(H3N2))

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • cytoplasmic mRNA processing body
  • cytosol
  • plasma

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Garre1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • Rac protein signal transduction

Cellular Component

Where in the cell the gene product is active
  • cytoplasmic mRNA processing body
  • cytosol

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • small GTPase binding

Gene-Specific Assays for Results You Can Trust

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