ELFN2 Gene Summary [Human]

Predicted to enable protein phosphatase inhibitor activity. Predicted to be involved in negative regulation of catalytic activity. Located in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
ELFN2
Official Name
extracellular leucine rich repeat and fibronectin type III domain containing 2 [Source:HGNC Symbol;Acc:HGNC:29396]
Ensembl ID
ENSG00000166897
Bio databases IDs NCBI: 114794 Ensembl: ENSG00000166897
Aliases extracellular leucine rich repeat and fibronectin type III domain containing 2
Synonyms 6330514E13, AW048948, Elfn2-ps1, extracellular leucine-rich repeat and fibronectin type III domain containing 2, KIAA1904, leucine rich repeat and fibronectin type III, extracellular 2, LRRC62, PPP1R29, RGD1559693, RP1 63G55, RP1-63G5.5
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ELFN2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein phosphatase 1 regulatory subunit 42
  • Leucine rich repeat
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • leprosy
regulated by
  • EZH2
  • Dengue virus 2 Thailand/NGS-C/1944
  • L-methionine
  • SLC7A5
role in cell
  • adhesion
  • synaptic transmission by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • synaptic membrane
  • nerve ending
  • synapse

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human ELFN2 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • extracellular space
  • membrane
  • extracellular matrix

Molecular Function

What the gene product does at the molecular level
  • protein phosphatase inhibitor activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.