Elfn2 Gene Summary [Mouse]
Predicted to enable protein phosphatase inhibitor activity. Involved in synaptic membrane adhesion. Acts upstream of or within chemical synaptic transmission; establishment of protein localization; and gene expression. Is active in postsynaptic density membrane. Is expressed in eye; intestine; male reproductive gland or organ; and nervous system. Orthologous to human ELFN2 (extracellular leucine rich repeat and fibronectin type III domain containing 2). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Elfn2 |
| Official Name | leucine rich repeat and fibronectin type III, extracellular 2 [Source:MGI Symbol;Acc:MGI:3608416] |
| Ensembl ID | ENSMUSG00000043460 |
| Bio databases IDs | |
| Aliases | leucine rich repeat and fibronectin type III, extracellular 2 |
| Synonyms | 6330514E13, AW048948, Elfn2-ps1, extracellular leucine-rich repeat and fibronectin type III domain containing 2, KIAA1904, leucine rich repeat and fibronectin type III, extracellular 2, LRRC62, PPP1R29, RGD1559693, RP1 63G55, RP1-63G5.5 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Elfn2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein phosphatase 1 regulatory subunit 42
- Leucine rich repeat
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- synaptic membrane
- nerve ending
- synapse
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Elfn2 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- extracellular space
- membrane
- extracellular matrix
Molecular Function
What the gene product does at the molecular level
- protein phosphatase inhibitor activity