PARM1 Gene Summary [Human]

Predicted to be involved in positive regulation of telomerase activity. Located in several cellular components, including Golgi apparatus; endosome; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
PARM1
Official Name
prostate androgen-regulated mucin-like protein 1 [Source:HGNC Symbol;Acc:HGNC:24536]
Ensembl ID
ENSG00000169116
Bio databases IDs NCBI: 25849 Ensembl: ENSG00000169116
Aliases prostate androgen-regulated mucin-like protein 1, Prostatic androgen-repressed message 1, Castration-induced prostatic apoptosis-related protein 1, WSC4, cell wall integrity and stress response component 4 homolog (S. cerevisiae)
Synonyms 2210012L08Rik, 9130213B05Rik, CIPAR-1, DKFZP564O0823, prostate androgen-regulated mucin-like protein 1, WSC4
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human PARM1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • PARM
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • idiopathic scoliosis
  • Waldenström macroglobulinemia
  • nephrosis
regulated by
  • GSTO1
  • levodopa
  • CGA
  • PRL
  • PAX7
  • AGN194204
  • BLM
  • progesterone
  • beta-estradiol
  • testosterone propionate

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • intracellular membrane-bounded organelle
  • Plasma Membrane
  • Golgi Apparatus
  • cytosol
  • nucleoplasm
  • early endosomes
  • late endosomes

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human PARM1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • positive regulation of telomerase activity

Cellular Component

Where in the cell the gene product is active
  • early endosome
  • intracellular membrane-bounded organelle
  • late endosome
  • cytosol
  • Golgi membrane
  • Golgi apparatus
  • endosome membrane
  • plasma membrane
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.