NMD3 Gene Summary [Human]

Ribosomal 40S and 60S subunits associate in the nucleolus and are exported to the cytoplasm. The protein encoded by this gene is involved in the passage of the 60S subunit through the nuclear pore complex and into the cytoplasm. Several transcript variants exist for this gene, but the full-length natures of only two have been described to date. [provided by RefSeq, Feb 2016]

Details

Type
Protein Coding
Official Symbol
NMD3
Official Name
NMD3 ribosome export adaptor [Source:HGNC Symbol;Acc:HGNC:24250]
Ensembl ID
ENSG00000169251
Bio databases IDs NCBI: 51068 Ensembl: ENSG00000169251
Aliases NMD3 ribosome export adaptor
Synonyms CGI-07, NMD3 ribosome export adaptor, RGD1308468
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human NMD3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • NMD3 family
  • protein binding activity, bridging
  • ribosomal large subunit binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
role in cell
  • autophagy in
  • autophagy

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • Cytoplasm
  • nucleoplasm
  • nucleoli

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human NMD3 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • ribosomal large subunit export from nucleus
  • positive regulation of protein binding
  • protein transport

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytoplasm
  • membrane
  • nucleolus
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • RNA binding
  • ribosomal large subunit binding
  • protein binding, bridging

Gene-Specific Assays for Results You Can Trust

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