RMC1 Gene Summary [Human]
This gene encodes a colon cancer associated protein. [provided by RefSeq, Jan 2013]
Details
| Type | Protein Coding |
| Official Symbol | RMC1 |
| Official Name | regulator of MON1-CCZ1 [Source:HGNC Symbol;Acc:HGNC:24326] |
| Ensembl ID | ENSG00000141452 |
| Bio databases IDs | |
| Aliases | regulator of MON1-CCZ1, colon cancer associated protein Mic1 |
| Synonyms | 2400010D15Rik, 3110002H16Rik, C18orf8, HsT2591, MIC1, regulator of MON1-CCZ1, RGD1311805, WDR98 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RMC1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- Colon cancer-associated protein Mic1-like
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- non-insulin-dependent diabetes mellitus
- preeclampsia
- pancreatic cancer
- chronic pancreatitis
regulated by
- 5-fluorouracil
- 4-hydroxycinnamyl aldehyde
- 2-amino-5-phosphonovaleric acid
- Ribosome 80S
- FCGR1A
role in cell
- cell death
- capivasertib resistance
- autophagy by
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- endosomal membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human RMC1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- autophagy
- regulation of autophagy
Cellular Component
Where in the cell the gene product is active
- late endosome membrane
- Mon1-Ccz1 complex
- lysosomal membrane
Molecular Function
What the gene product does at the molecular level
- protein binding