DCDC1 Gene Summary [Human]

This gene encodes a member of the doublecortin family. The protein encoded by this gene is a hydrophilic, intracellular protein. It contains a single doublecortin domain and is unable to bind microtubules and to regulate microtubule polymerization. This gene is mainly expressed in adult testis. It does not have a mouse homolog. [provided by RefSeq, Sep 2010]

Details

Type
Nonsense Mediated Decay
Official Symbol
DCDC1
Official Name
doublecortin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20625]
Ensembl ID
ENSG00000170959
Bio databases IDs NCBI: 341019 Ensembl: ENSG00000170959
Aliases doublecortin domain containing 1
Synonyms 4732421G10Rik, DCDC5, doublecortin domain containing 1, doublecortin domain containing 5, EG436559, FLJ46154, Gm9342, LOC100288976, LOC100291414, LOC100293627, LOC100293660, LOC341019
Species
Human, Homo sapiens
OrthologiesMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human DCDC1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • microtubule binding
  • Ricin-type beta-trefoil
  • Ubl1_cv_Nsp3_N-like
  • protein binding
  • ricin B-type lectin domain, beta-trefoil fold

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • hypertension
  • osteoarthritis
  • major depression
  • systemic lupus erythematosus
  • insomnia
  • severe COVID-19
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • midbody
  • Flemming body
  • mitotic spindle

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human DCDC1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cell division
  • intracellular signal transduction

Cellular Component

Where in the cell the gene product is active
  • mitotic spindle
  • cytoplasm
  • midbody
  • microtubule

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • carbohydrate binding
  • microtubule binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.