SLC25A33 Gene Summary [Human]
SLC25A33 belongs to the SLC25 family of mitochondrial carrier proteins (Haitina et al., 2006 [PubMed 16949250]).[supplied by OMIM, Mar 2008]
Details
| Type | Protein Coding |
| Official Symbol | SLC25A33 |
| Official Name | solute carrier family 25 member 33 [Source:HGNC Symbol;Acc:HGNC:29681] |
| Ensembl ID | ENSG00000171612 |
| Bio databases IDs | |
| Aliases | solute carrier family 25 member 33 |
| Synonyms | 5730438N18Rik, BMSC-MCP, LOC686808, PNC1, solute carrier family 25 member 33, solute carrier family 25, member 33 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SLC25A33 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Mitochondrial carrier protein
- pyrimidine nucleotide transporter
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- facioscapulohumeral muscular dystrophy
role in cell
- proliferation
- expression in
- phosphorylation in
- growth
- biogenesis
- epithelial-mesenchymal transition
- organization
- biogenesis in
- assembly in
- replication in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SLC25A33 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- transcription from mitochondrial promoter
- cellular response to insulin stimulus
- positive regulation of cell growth
- mitochondrial respiratory chain complex III assembly
- regulation of mitochondrial membrane potential
- regulation of oxidative phosphorylation
- positive regulation of cell proliferation
- mitochondria-nucleus signaling pathway
- pyrimidine nucleotide transport
- mitochondrion organization
- mitochondrial genome maintenance
Cellular Component
Where in the cell the gene product is active
- mitochondrial membrane
- mitochondrion
- mitochondrial inner membrane
Molecular Function
What the gene product does at the molecular level
- pyrimidine nucleotide transmembrane transporter activity