LRRC10 Gene Summary [Human]

Predicted to enable actin binding activity. Predicted to be involved in cardiac muscle cell development. Predicted to be located in myofibril. Predicted to be active in cytoskeleton and sarcomere. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
LRRC10
Official Name
leucine rich repeat containing 10 [Source:HGNC Symbol;Acc:HGNC:20264]
Ensembl ID
ENSG00000198812
Bio databases IDs NCBI: 376132 Ensembl: ENSG00000198812
Aliases leucine rich repeat containing 10, heart-restricted leucine-rich repeat protein
Synonyms D330003I11Rik, HRLRRP, leucine-rich repeat-containing 10, LOC100911101, LRRC10A, Serdin1
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human LRRC10 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein phosphatase 1 regulatory subunit 42
  • actinin binding
  • actin binding
  • Leucine rich repeat

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • dilated cardiomyopathy
  • cardiac hypertrophy
regulated by
role in cell
  • cytokinesis
  • abnormal morphology
  • development
  • binucleation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • cytoskeleton
  • Mitochondria
  • sarcomere
  • myofibrils

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human LRRC10 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cardiac muscle cell development

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytoskeleton
  • mitochondrion
  • sarcomere

Molecular Function

What the gene product does at the molecular level
  • actin binding
  • alpha-actinin binding

Gene-Specific Assays for Results You Can Trust

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