Slc25a33 Gene Summary [Rat]

Predicted to enable pyrimidine nucleotide transmembrane transporter activity. Predicted to be involved in several processes, including cellular response to peptide hormone stimulus; mitochondria-nucleus signaling pathway; and mitochondrion organization. Predicted to be located in mitochondrial membrane. Orthologous to human SLC25A33 (solute carrier family 25 member 33). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Slc25a33
Official Name
solute carrier family 25 member 33 [Source:RGD Symbol;Acc:1583942]
Ensembl ID
ENSRNOG00000016949
Bio databases IDs NCBI: 691431 Ensembl: ENSRNOG00000016949
Aliases solute carrier family 25 member 33
Synonyms 5730438N18Rik, BMSC-MCP, LOC686808, PNC1, solute carrier family 25 member 33, solute carrier family 25, member 33
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Slc25a33 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Mitochondrial carrier protein
  • pyrimidine nucleotide transporter
  • transporter

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • facioscapulohumeral muscular dystrophy
regulated by
regulates
  • reactive oxygen species
  • Cytochrome bc1
  • GABPA
  • ACAC
  • PRKAA
  • mitochondrial DNA
  • PPARGC1A
  • UDP-N-acetylglucosamine
role in cell
  • proliferation
  • expression in
  • phosphorylation in
  • growth
  • biogenesis
  • epithelial-mesenchymal transition
  • organization
  • biogenesis in
  • assembly in
  • replication in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Mitochondria
  • mitochondrial membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Slc25a33 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • transcription from mitochondrial promoter
  • cellular response to insulin stimulus
  • positive regulation of cell growth
  • mitochondrial respiratory chain complex III assembly
  • regulation of mitochondrial membrane potential
  • regulation of oxidative phosphorylation
  • positive regulation of cell proliferation
  • mitochondria-nucleus signaling pathway
  • pyrimidine nucleotide transport
  • mitochondrion organization
  • mitochondrial genome maintenance

Cellular Component

Where in the cell the gene product is active
  • mitochondrial membrane
  • mitochondrion
  • mitochondrial inner membrane

Molecular Function

What the gene product does at the molecular level
  • pyrimidine nucleotide transmembrane transporter activity

Gene-Specific Assays for Results You Can Trust

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