ENDOV Gene Summary [Human]
Enables DNA binding activity; endoribonuclease activity, producing 5'-phosphomonoesters; and single-stranded RNA binding activity. Predicted to be involved in DNA repair. Located in cytoplasmic stress granule and nucleolus. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Retained Intron |
| Official Symbol | ENDOV |
| Official Name | endonuclease V [Source:HGNC Symbol;Acc:HGNC:26640] |
| Ensembl ID | ENSG00000173818 |
| Bio databases IDs | |
| Aliases | endonuclease V |
| Synonyms | A730011L01Rik, endonuclease V, FLJ35220 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ENDOV often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- endonuclease V
- 5' phosphomonoester producing endodeoxyribonuclease
- enzyme
- protein binding
- magnesium ion binding
- 5' phosphomonoester producing endoribonuclease
- single-stranded RNA binding
- DNA binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- nucleoli
- stress granule
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ENDOV gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- DNA repair
Cellular Component
Where in the cell the gene product is active
- cytoplasmic stress granule
- cytoplasm
- nucleolus
Molecular Function
What the gene product does at the molecular level
- magnesium ion binding
- DNA binding
- endodeoxyribonuclease activity, producing 5'-phosphomonoesters
- protein binding
- single-stranded RNA binding
- endoribonuclease activity, producing 5'-phosphomonoesters