MRPL11 Gene Summary [Human]
This nuclear gene encodes a 39S subunit component of the mitochondial ribosome. Alternative splicing results in multiple transcript variants. Pseudogenes for this gene are found on chromosomes 5 and 12. [provided by RefSeq, May 2014]
Details
| Type | Protein Coding |
| Official Symbol | MRPL11 |
| Official Name | mitochondrial ribosomal protein L11 [Source:HGNC Symbol;Acc:HGNC:14042] |
| Ensembl ID | ENSG00000174547 |
| Bio databases IDs | |
| Aliases | mitochondrial ribosomal protein L11 |
| Synonyms | 2410001P07Rik, CGI-113, L11MT, LOC101928090, mitochondrial ribosomal protein L11, uL11m |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human MRPL11 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- structural constituent of ribosome
- Ribosomal protein L11, RNA binding domain
- Ribosomal protein L11/L12
- Ribosomal protein L11, N-terminal domain
- protein binding
- Ribosomal_L11
- 50S ribosomal protein uL11, bacterial form
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- ribosome
- Mitochondria
- mitochondrial inner membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human MRPL11 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- mitochondrial translation
- translation
Cellular Component
Where in the cell the gene product is active
- mitochondrion
- mitochondrial ribosome
- mitochondrial large ribosomal subunit
- mitochondrial inner membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding
- structural constituent of ribosome
- LSU rRNA binding