KCTD2 Gene Summary [Human]
Predicted to enable cullin family protein binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of Cul3-RING ubiquitin ligase complex. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Processed Transcript |
| Official Symbol | KCTD2 |
| Official Name | potassium channel tetramerization domain containing 2 [Source:HGNC Symbol;Acc:HGNC:21294] |
| Ensembl ID | ENSG00000180901 |
| Bio databases IDs | |
| Aliases | potassium channel tetramerization domain containing 2 |
| Synonyms | 2310012I15Rik, KIAA0176, LOC101928375, potassium channel tetramerisation domain containing 2, potassium channel tetramerization domain containing 2, RGD1566063 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human KCTD2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- binding protein
- Broad-Complex, Tramtrack and Bric a brac
- BTB_POZ
- protein binding
- ion channel
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human KCTD2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- proteasomal ubiquitin-dependent protein catabolic process
- protein homooligomerization
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- Cul3-RING ubiquitin ligase complex