LSM10 Gene Summary [Human]

Enables U7 snRNA binding activity. Involved in positive regulation of G1/S transition of mitotic cell cycle. Located in Cajal body. Part of U7 snRNP. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Processed Transcript
Official Symbol
LSM10
Official Name
LSM10, U7 small nuclear RNA associated [Source:HGNC Symbol;Acc:HGNC:17562]
Ensembl ID
ENSG00000181817
Bio databases IDs NCBI: 84967 Ensembl: ENSG00000181817
Aliases LSM10, U7 small nuclear RNA associated
Synonyms LSM10, U7 small nuclear RNA associated, MST074, MSTP074, U7 snRNP-specific Sm-like protein LSM10
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human LSM10 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • snRNA binding
  • Sm and related proteins
  • protein binding
  • RNA binding

Pathways

Biological processes and signaling networks where the LSM10 gene in human plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • diverticulitis
regulated by
regulates
role in cell
  • expression in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nucleoplasm
  • nuclear bodies
  • Cajal bodies

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human LSM10 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • RNA splicing
  • positive regulation of G1/S transition of mitotic cell cycle
  • histone mRNA 3'-end processing

Cellular Component

Where in the cell the gene product is active
  • nuclear body
  • cytoplasmic U snRNP body
  • Cajal body
  • U7 snRNP
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • histone pre-mRNA DCP binding
  • U7 snRNA binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.