CTAG1B Gene Summary [Human]
The protein encoded by this gene is an antigen that is overexpressed in many cancers but that is also expressed in normal testis. This gene is found in a duplicated region of the X-chromosome and therefore has a neighboring gene of identical sequence. [provided by RefSeq, Jan 2012]
Details
| Type | Protein Coding |
| Official Symbol | CTAG1B |
| Official Name | cancer/testis antigen 1B [Source:HGNC Symbol;Acc:HGNC:2491] |
| Ensembl ID | ENSG00000184033 |
| Bio databases IDs | |
| Aliases | cancer/testis antigen 1B |
| Synonyms | cancer/testis antigen 1B, CT6.1, CTAG, CTAG1, ESO1, LAGE-2, LAGE2B, NY-ESO-1 |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CTAG1B often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Transcription factor Pcc1
- protein binding
- identical protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- ovarian cancer
- neuroblastoma
- neuroblastoma formation
- synovial sarcoma
- soft tissue sarcoma cancer
role in cell
- expression in
- stimulation
- activation
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- Cytoplasm
- cell surface
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human CTAG1B gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- threonylcarbamoyladenosine metabolic process
Cellular Component
Where in the cell the gene product is active
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding