Tmprss11b Gene Summary [Rat]

Predicted to enable serine-type peptidase activity. Predicted to be involved in proteolysis. Predicted to be located in plasma membrane. Orthologous to human TMPRSS11B (transmembrane serine protease 11B). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Tmprss11b
Official Name
transmembrane serine protease 11B [Source:RGD Symbol;Acc:1303278]
Ensembl ID
ENSRNOG00000002002
Bio databases IDs NCBI: 365265 Ensembl: ENSRNOG00000002002
Aliases transmembrane serine protease 11B
Synonyms HATL5, Tmprss11bnl, transmembrane serine protease 11B
Species
Rat, Rattus norvegicus
OrthologiesHuman

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Tmprss11b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Trypsin-like serine protease
  • trypsin
  • Tryp_SPc
  • serine-type peptidase
  • peptidase
  • SEA domain

Pathways

Biological processes and signaling networks where the Tmprss11b gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • keratocystic odontogenic tumor
  • keratocystic odontogenic tumors

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Plasma Membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Tmprss11b gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • proteolysis

Cellular Component

Where in the cell the gene product is active
  • extracellular vesicular exosome
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • serine-type peptidase activity
  • serine-type endopeptidase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.