MAGEE2 Gene Summary [Human]
This gene encodes a member of the E subfamily of MAGE (melanoma antigen-encoding gene) gene family. The gene is intronless and the encoded protein has two of the MAGE domains which are characteristic of MAGE family proteins. [provided by RefSeq, Sep 2011]
Details
| Type | Protein Coding |
| Official Symbol | MAGEE2 |
| Official Name | MAGE family member E2 [Source:HGNC Symbol;Acc:HGNC:24935] |
| Ensembl ID | ENSG00000186675 |
| Bio databases IDs | |
| Aliases | MAGE family member E2, Melanoma-associated antigen E2, Hepatocellular carcinoma-associated protein 3 |
| Synonyms | 9630059J11, 9630059J11Rik, BB131182, HCA3, MAGE family member E2, RGD1564872 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human MAGEE2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- MAGE homology domain
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human MAGEE2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of transcription from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- nucleus