LYPD6 Gene Summary [Human]
Members of the LY6 protein family (see SLURP1; MIM 606119), such as LYPD6, have at least one 80-amino acid LU domain that contains 10 conserved cysteines with a defined disulfide-bonding pattern (Zhang et al., 2010 [PubMed 19653121]).[supplied by OMIM, Apr 2010]
Details
| Type | Protein Coding |
| Official Symbol | LYPD6 |
| Official Name | LY6/PLAUR domain containing 6 [Source:HGNC Symbol;Acc:HGNC:28751] |
| Ensembl ID | ENSG00000187123 |
| Bio databases IDs | |
| Aliases | LY6/PLAUR domain containing 6 |
| Synonyms | E130115E03Rik, LOC100365115, LOC682476, LY6/PLAUR domain containing 6 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human LYPD6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- acetylcholine receptor inhibitor
- protein binding
- TFP
- acetylcholine receptor regulator
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- cellular membrane
- neurites
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human LYPD6 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of canonical Wnt receptor signaling pathway
Cellular Component
Where in the cell the gene product is active
- dendrite
- cytoplasm
- membrane raft
- synapse
- perikaryon
- extracellular region
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- acetylcholine receptor inhibitor activity