ZBTB44 Gene Summary [Human]
Predicted to enable DNA binding activity and metal ion binding activity. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | ZBTB44 |
| Official Name | zinc finger and BTB domain containing 44 [Source:HGNC Symbol;Acc:HGNC:25001] |
| Ensembl ID | ENSG00000196323 |
| Bio databases IDs | |
| Aliases | zinc finger and BTB domain containing 44 |
| Synonyms | 6030404E16RIK, BC038156, BTBD15, E230011F09, HSPC063, RGD1308984, zinc finger and BTB domain containing 44, ZNF851 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ZBTB44 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Zinc finger, C2H2 type
- zinc finger
- Broad-Complex, Tramtrack and Bric a brac
- Zinc-finger double domain
- BTB_POZ
- BTB/POZ domain
- protein binding
- C2H2-type zinc finger
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- Huntington disease
- neoplasia
- renal cell carcinoma
- renal cell cancer
regulated by
- maneb
- paraquat
- D-glucose
- pyridaben
- HNRNPC
- peripheral blood neutrophils
regulates
role in cell
- expression in
- proliferation
- migration
- cell viability
- M2 polarization
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ZBTB44 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- nucleus
Molecular Function
What the gene product does at the molecular level
- DNA binding
- protein binding
- metal ion binding