YRDC Gene Summary [Human]

Predicted to enable nucleotidyltransferase activity and tRNA binding activity. Acts upstream of or within negative regulation of transport. Predicted to be located in membrane and mitochondrion. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
YRDC
Official Name
yrdC N6-threonylcarbamoyltransferase domain containing [Source:HGNC Symbol;Acc:HGNC:28905]
Ensembl ID
ENSG00000196449
Bio databases IDs NCBI: 79693 Ensembl: ENSG00000196449
Aliases yrdC N6-threonylcarbamoyltransferase domain containing, ischemia/reperfusion inducible protein
Synonyms AV303379, BC023823, DRIP3, FLJ23476, GAMOS10, IRIP, Isrip, ITIP, LOC319113, SUA5, yrdC domain containing (E.coli), yrdC N(6)-threonylcarbamoyltransferase domain containing, yrdC N6-threonylcarbamoyltransferase domain containing
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human YRDC often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Carbamoyltransferase C-terminus
  • nucleotidyltransferase
  • enzyme
  • protein binding
  • Telomere recombination

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • Galloway-Mowat syndrome type 10
regulated by
  • MYC
  • Salmonella enterica serotype abortus equi lipopolysaccharide
  • TREM1
regulates
  • 1-methyl-4-phenylpyridinium
  • SLC22A1

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cellular membrane
  • Mitochondria

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human YRDC gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • regulation of translational fidelity
  • negative regulation of transport

Cellular Component

Where in the cell the gene product is active
  • cytoplasm
  • mitochondrion
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • nucleotidyltransferase activity
  • protein binding
  • double-stranded RNA binding
  • tRNA binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.