Yrdc Gene Summary [Mouse]
Predicted to enable L-threonylcarbamoyladenylate synthase and tRNA binding activity. Predicted to be involved in regulation of translational fidelity and tRNA threonylcarbamoyladenosine modification. Predicted to act upstream of or within negative regulation of transport. Located in membrane. Human ortholog(s) of this gene implicated in Galloway-Mowat syndrome. Orthologous to human YRDC (yrdC N6-threonylcarbamoyltransferase domain containing). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Yrdc |
| Official Name | yrdC domain containing (E.coli) [Source:MGI Symbol;Acc:MGI:2387201] |
| Ensembl ID | ENSMUSG00000028889 |
| Bio databases IDs | |
| Aliases | yrdC domain containing (E.coli) |
| Synonyms | AV303379, BC023823, DRIP3, FLJ23476, GAMOS10, IRIP, Isrip, ITIP, LOC319113, SUA5, yrdC domain containing (E.coli), yrdC N(6)-threonylcarbamoyltransferase domain containing, yrdC N6-threonylcarbamoyltransferase domain containing |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Yrdc often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Carbamoyltransferase C-terminus
- nucleotidyltransferase
- enzyme
- protein binding
- Telomere recombination
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
- Mitochondria
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Yrdc gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of translational fidelity
- negative regulation of transport
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- mitochondrion
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- nucleotidyltransferase activity
- protein binding
- double-stranded RNA binding
- tRNA binding