CEP76 Gene Summary [Human]
This gene encodes a centrosomal protein which regulates centriole amplification by limiting centriole duplication to once per cell cycle. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | CEP76 |
| Official Name | centrosomal protein 76 [Source:HGNC Symbol;Acc:HGNC:25727] |
| Ensembl ID | ENSG00000101624 |
| Bio databases IDs | |
| Aliases | centrosomal protein 76 |
| Synonyms | 6230425F05Rik, 9630013E05, C18orf9, centrosomal protein 76, CSG11, HsT1705, RGD1305183 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CEP76 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- CEP76 C2 domain
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- centrosome
- centriole
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human CEP76 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of centriole replication
Cellular Component
Where in the cell the gene product is active
- centrosome
- centriole
- cytosol
- macromolecular complex
Molecular Function
What the gene product does at the molecular level
- protein binding