SOX2-OT Gene Summary [Human]
This gene produces alternatively spliced long non-coding RNAs. These RNAs were observed to be upregulated in tumor cells and positively correlated to expression of the SRY-box 2 gene. Overexpression of these transcripts may promote cell proliferation. [provided by RefSeq, Dec 2017]
Details
| Type | Long Non-Coding RNA |
| Official Symbol | SOX2-OT |
| Official Name | SOX2 overlapping transcript [Source:HGNC Symbol;Acc:HGNC:20209] |
| Ensembl ID | ENSG00000242808 |
| Bio databases IDs | |
| Aliases | SOX2 overlapping transcript, non-protein coding RNA 43 |
| Synonyms | NCRNA00043, SOX2 overlapping transcript |
| Species | Human, Homo sapiens |
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
- SOX3
- mir-8 (includes others)
disease
- COVID-19
- schizophrenia
- insomnia
- organismal death
- pancreatic ductal adenocarcinoma
- pancreatic epithelial cancer
- ductal pancreatic cancer
- lung cancer
- cataract
- major depression
role in cell
- migration
- apoptosis
- expression in
- proliferation
- cell viability
- proportion
- cell cycle progression
- invasion by
- growth rate
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown